Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigen in sputum from patients with lower respiratory tract infection Running title: Detecting S. pneumoniae antigen in sputum
نویسندگان
چکیده
Author(s) Izumikawa, Koichi; Akamatsu, Suguru; Kageyama, Akiko; Okada, Kiyomi; Kazuyama, Yukumasa; Takayanagi, Noboru; Nakamura, Shigeki; Inoue, Yuichi; Higashiyama, Yasuhito; Fukushima, Kiyoyasu; Ishida, Tadashi; Sawai, Toyomitsu; Yoshimura, Kunihiko; Nakahama, Chikara; Ohmichi, Mitsuhide; Kakugawa, Tomoyuki; Nishioka, Yasuhiko; Aoki, Nobuki; Seki, Masafumi; Kakeya, Hiroshi; Yamamoto, Yoshihiro; Yanagihara, Katsunori; Kohno, Shigeru
منابع مشابه
Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigen in sputum samples from patients with lower respiratory tract infection.
A novel, rapid, and noninvasive test (ODK0501) to detect Streptococcus pneumoniae antigen was evaluated in a Japanese multicenter study. ODK0501 uses polyclonal antibodies to detect C polysaccharide of S. pneumoniae from sputum samples by an immunochromatographic assay. The utility of ODK0501 was evaluated for 161 adult patients with lower respiratory tract infection between March 2006 and Marc...
متن کاملEvaluation of the rapid immunochromatographic ODK0501 assay for Streptococcus pneumoniae antigen detection with nasopharyngeal swabs: preliminary report
BACKGROUND Early identification and control of pathogenic bacteria are important in the treatment of pneumonia. Currently, two rapid antigen detection kits for pneumococcal pneumonia are available: one uses urine samples and the other, named RAPIRUN® S. pneumoniae, uses sputum samples. RAPIRUN® has shown high sensitivity with nasopharyngeal swab samples from pediatric patients. In this study, w...
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The lower respiratory tract is vulnerable to infection by a wide variety of microorganisms, because it is one of the organ systems which communicate directly with the environments. Although viruses and fungi can cause lower respiratory tract infections, bacteria are the dominant pathogens. Among bacteria the common causes of lower respiratory tract infection is Streptococcus pneumoniae, Mycopla...
متن کاملDiagnosis of Streptococcus pneumoniae pneumonia by quantitative enzyme linked immunosorbent assay of C-polysaccharide antigen.
AIMS To evaluate the use of a quantitative enzyme linked immunosorbent assay (ELISA) detecting C-polysaccharide (PnC) antigen in sputum for the diagnosis of Streptococcus pneumoniae infection. METHODS Specimens of sputum from 60 patients with acute community and hospital acquired pneumonia and infective exacerbations of obstructive airways disease were examined by semiquantitative culture and...
متن کاملDiagnostic value of urinary antigen Streptococcus pneumoniae in children With pneumonia: A case control study
Abstract Background and objectives: The aim of this study was the detection of S.pneumoniae infection by rapid urinary test and blood culture in children with pneumonia in comparison with healthy children. Material and Methods: This case control study was carried out in pediatric ward of Rasoul Akram hospital in Tehran, Iran (2006 - 200٧).Fifty-four Community acquired pneumonia (CAP) and 50 hea...
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